This was 16.1 percent lower than the state average of 38.9 percent. In 2020 the total municipality population reached 674.
80.9 percent of the population had at least a high school diploma or the equivalent.
Degree distribution in Mayesville for 2020*
| Degree | Number of people | Percentage of population |
|---|---|---|
| No degree | 87 | 19.1 |
| Regular high school diploma | 153 | 33.6 |
| GED or alternative credential | 27 | 5.9 |
| Some college, less than 1 year | 20 | 4.4 |
| Some college, 1 or more years, no degree | 65 | 14.3 |
| Associate's degree | 28 | 6.1 |
| Bachelor's degree | 35 | 7.7 |
| Master's degree | 39 | 8.6 |
| Professional school degree | 2 | 0.4 |
| Doctorate degree | 0 | 0 |
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